Vitiligo White Spots on Skin Depigmentation or loss of pigment producing cells is the major cause towards developing of white patches on skin. Our skin has specialized cells which are known as melanocytes. The melanocytes are the cells that produce melanin for maintaining of human skin color. It also acts as a sunscreen that protects the skin from ultraviolet rays of sun. Melanin can be found in the outermost layer of the skin. Vitiligo white spots and white patches on skin is a disorder which occurs where melanocytes, the cells that produce melanin, die off. When the pigment cells are destroyed, white spots and white patches appear on the skin. photo credit: wolfgang.wedenig via photopin cc Common Causes of Vitiligo Others factors that are associated with depigmentation in skin cells, includes the following: Physical and Mental Stress Physical, mental and emotional stress is considered one of the major causes of vitiligo . mental stress like death of relatives, break ...